In Vitro Fertilization (IVF)

Infertility is a dark, lonely situation which is hard to experience. It is difficult to live with the reality which comes with the countless trying, investigations and failure to conceive even after the various procedures. Medical science with its increasing advances has created a reproductive assistance to the infertile couples. In Vitro Fertilization or popularly known as IVF wherein the egg and sperm are fertilized in a laboratory dish and then transferred to the uterus.

Sir Robert Edwards and Patrick Steptoe are the pioneers of IVF in 1978. Louise Brown is the first test tube baby born by IVF. Infertility can be due to both male and female factors which needs to be assessed carefully.

Which are the couples who can go for In Vitro Fertilization?

IVF can be useful in the patients with following conditions:

  • Women with blocked fallopian tubes
  • Male having low sperm count or abnormal structure and motility of sperms
  • Women with Endometriosis , ovarian failure, and ovulation disorders
  • Couples having genetic diseases in which conceiving is difficult
  • Unexplained infertility

What are the procedures of In Vitro Fertilization?

A couple has to undergo five steps  in IVF:

  1. Stimulation of ovaries for egg production:

Fertility drugs are given to stimulate the ovaries for ovulation or known as egg production. Normally, only one egg is released from ovaries.  Fertility drugs cause the ovaries to produce many eggs. Follicular studies are done to monitor the follicular growth and development through transvaginal ultrasounds.  Blood tests are also done to check levels of hormones.

  1. Retrieving of  eggs

A small outpatient procedure is carried out to retrieve the eggs/follicular fluid aspiration from woman’s ovaries .The woman is put under anaesthesia. There is continuous monitoring of the woman’s reproductive system by ultrasound imaging. The doctor inserts a needle connected to a suction device into the vagina and then in the follicles of ovary. The device pulls the eggs from the follicles one by one. This step is repeated with the other ovary

In cases where a woman cannot produce their own eggs, they are taken  from egg donors from ART banks

  1. Combining and fertilization:

The combining of the sperm and the egg is known as insemination. This is stored in a controlled temperature in the laboratory. Fertilization occurs when the sperm enters an egg which happens within few hours.

Intracytoplasmic sperm injection (ICSI) is the process where the sperm is directly injected into the egg. This is carried out when the chances of fertilization might be low.

  1. Embryo culture:

Division of the fertilized egg results into an embryo. A constant check is done on the growth of the embryo. A normal and healthy embryo is which divides actively. If there are chances of a strong genetic disorder transferring to the child, a pre-implantation genetic diagnosis (PGD) is done 3-4 days after fertilization. Genetic material from the embryo is screened for the disorders.

  1. Embryo transfer:

The final and important step in IVF is placing the embryos in the uterus after about 3 to 5 days from fertilization.
A catheter (thin tube) containing the embryos is inserted through the vagina, then cervix and up into the uterus. The woman is awake during this procedure.
When the embryo gets implanted in the uterine lining and grows,  woman gets pregnant.
Chances of twins, triplets increase when more than one embryo is transferred into the uterus. Doctors can store the unused extra embryos in frozen form . If first embryo transfer fails , frozen embryos can later be used in next attempt .

What are the benefits of In Vitro Fertilization and why should couples consider IVF?

  1.   When couples  who are trying to conceive are tired with the various failed infertility treatments, IVF techniques offers them their best chances for success. Due to everincreasing developments and new technology in the field  of this  procedure,  IVF success rates are now even better.
  2.  IVF is also used during surrogacy especially for  woman who is physically unfit to carry a full-term pregnancy .
  3. IVF is carried out in couples who have a low ovarian reserve or low or nil sperm count. In such cases donated eggs/sperms are used for IVF and the pregnancy chances increase with donor gametes
  4. Couples who are much focused on careers can store (cryopreservation) their eggs and sperms to carry out IVF in future.
  5. IVF decreases the chances of genetic disorders (Down’s syndrome, sickle cell anemia to name a few) due to PGD carried out during the procedure. Hence the possibility of healthy baby increases.
  6. IVF has reduced the number of abortions which occurs most often due to genetic abnormality.
  7. PCOS is the most common cause of hormonal imbalance and irregular ovulation in females. IVF has been successful in such cases where the ovulation is facilitated by giving fertility drugs.
  8. Women aged more than 40 years having low ovarian reserve are the suitable patients for in vitro fertilization.

Even though with many benefits of in vitro fertilization, there are few complications which can occur. Fertility medicines may give rise to abdominal pain, headaches, acidity, mood swings and bloating. Over-response to these medicines in rare circumstances can cause ovarian hyper-stimulation syndrome (OHSS ).

Success rate of IVF:

IVF has been noted to have a high success rate over other assisted reproductive technology. However, IVF may not be successful in each and every case.

Risks associated with IVF procedure:

There is a chance of bleeding, rupture of bowel or bladder and infection during egg retrieval step.

IVF carries a risk of multiple pregnancy when many embryos are transferred which in turn may give rise to low birth weight baby and premature delivery.

The major impact of in vitro fertilization on patients is on their finances due to its high cost. Emotionally couples are drained in case of In Vitro Fertilization failure.

Know about Infertility Treatment with Dr Shivani Sachdev Gour: How Safe & Successful It Is?

Infertility is a kind of disease related to reproductive system that harms a person’s ability to reproduce. Many women are suffering from the same problem and they have been diagnosed with female infertility. The problem is a serious concern for the couples because they cannot enjoy the parenthood. To overcome this problem, many people are desperate to find the treatment, which will enable them to have babies. Well In vitro fertilization or IVF is one such treatment that is being practiced to treat the infertility problem.

 

Advantages and Disadvantages of IVF Treatment

In the IVF treatment procedure works by perfectly collecting the sperm and the eggs from a couple, or the donor eggs and/or sperm. Then both the collected sperm and eggs are processed in a laboratory to create embryos. The embryos are then transferred to the uterus thereby helping the woman get pregnant. During IVF process, your doctor has to use some infertility drugs before your procedure and this can raise the chances of conceiving multiple babies. Besides, the drugs can also increase the risk of ovarian hyper stimulation syndrome. Let us discuss on the advantages and disadvantages of IVF treatment:

 

Advantages of IVF Treatment

Talking about the advantages offered by IVF can be unbelievable. Those couples that are facing infertility problem and those who are struggling to get pregnant IVF shows them the right path to get pregnant. Those are frustrated by the problem of unable to conceive naturally due to the reasons like stress, anxiety or depression, IVF offers them the best way to achieve their goals. Today, the process is being done for thousands of couples around the world.

 

In this concern, Intracytoplasmic injection of sperm, genetic counseling as well as assisted hatching can easily help in improving the maximum chances of success and getting pregnant. Some of the people even choose to freeze the embryos, which can be used in the future cycles. This is one such procedure that also carries the higher success rate compared to other procedures like artificial insemination.

 

Disadvantages of IVF Treatment

One of the main disadvantages of IVF treatment is that it is not guaranteed. The chances of success may vary greatly and that totally depends on different factors like the age of the woman. It is said that women who are over the age of 35 will not have the same chances of success compared to the women who are under the age of 35. The next is the higher cost of the procedure, which means that middle class people will not be able to get this treatment. Besides, freezing the embryos might also help to reduce the cost of future cycles.

 

One of the main disadvantage is the there is a risk of getting multiple pregnancies with IVF. Since the success is not guaranteed, doctors would transfer more than one embryo to the uterus for implantation with a hope that one of the embryos will successfully implant in the uterine wall and develop. The process can be opposite and in some cases, more than one embryo can get implanted and multiple pregnancies can be experienced.

 

So, now you might be thinking is IVF safe for mother? I would say, if you want to enjoy the life of being a parent, you can always give it a try. There are different many IVF Center in India, which you can approach but, I would refer you SCI Healthcare and SCI IVF Hospital and Multispecialty Centre. It is in Delhi, India, where the Infertility Treatment Cost is also affordable and Dr. Shivani Sachdev Gour is leading this center.

 

Know who Dr. Shivani Sachdev Gour is?

Dr. Shivani Sachdev Gour is an MBBS, MD – Obstetrics & Gynaecology, DNB – Medical Genetics. She is a Gynecologist, Obstetrician and Infertility Specialist, who has 17 Years of experience in this genre. Dr Shivani Sachdev has completed her medical and Obstetrical qualifications from Mumbai in the year 2000. She has also spent her 4 years in the UK, where she practiced as an IVF clinical research fellow at the prestigious Hammersmith Hospital. She has also trained herself as a Gynecologist and Obstetrician at Royal Infirmary of Edinburgh.

 

After completing the practices, she returned to Delhi and has opened SCI Healthcare and SCI IVF Hospital and Multispecialty Centre. Now Dr. Shivani is the founder and director of this center, where she also gives consultation about the fertility specialist. She is also leading the SCI Healthcare and SCI IVF Hospital surrogacy and IVF programs.

Dr. Shivani Sachdev Gour: A Trustworthy Obstetrician and Gynecologist in Delhi

You might have met many couples who don’t have any offspring even after 2 to 3 years of marriage. The reason is infertility which is explained as not getting pregnant even after having carefully timed and unprotected sex for one year. Any issue related to such issues can be resolved because nowadays there are many clinical ways that can help you get pregnant and let you enjoy the phase of parenthood.

 

You can meet with infertility specialists namely Dr. Shivani Sachdev Gour, who is one of the prominent Obstetrician and Gynecologist in Delhi. She has practiced as an Obstetrician & Gynecologist and even as Infertility Specialist for the past 16 years. She has completed her medical and Obstetrical qualifications from Mumbai in the year 2000. She was also involved with the treating of the first cases of legal surrogacy in India. Talking about her expertise; she has spent four years in the United Kingdom and worked as an IVF clinical research fellow at the prestigious Hammersmith Hospital.

 

She has also practiced as a Gynecologist and Obstetrician at Royal Infirmary of Edinburgh, where she has gained membership of the Royal College of Obstetricians and Gynaecologists (UK) in May 2005. After this, she has returned to Delhi in the year 2007 in order to consult with an IVF specialist with Delhi’s premier Infertility treatment centers. With all her dexterous and expertise, she now leads the SCI Healthcare and SCIIVF Hospital surrogacy and IVF programs.

 

Benefits of IVF

IVF is very beneficial as it can help conceive and let you enjoy the time of parenthood. The ultimate advantage of IVF is to achieve a successful pregnancy and a healthy baby. IVF can help in making the reality for those people who were unable to have a baby for a long time.

  • IVF can bring up the best opportunity of having a child by using their own eggs
  • Through IVF the chance of older patients conceiving can also be increased. Moreover, the process focuses on using quality of eggs as well.
  • IVF also proved to very successful in patients with PCOS
  • IVF treatment can also be done by using donor egg

 

If a patient would require advanced technological assistance in IVF, the cost would be a bit higher. For ICSI treatment it will require an additional Rs. 1,50,000 to Rs. 2,50,000 and for FET (Frozen Embryo Transfer) procedure will cost about Rs. 1,20,000, apart from the IVF cost in India.